GLP‑1 treatment safety
Some questions belong in a conversation with your prescriber, pharmacist or healthcare team. These guides help you find the source information on medical history, other treatment, pregnancy and symptoms that need attention.
A place to start
What should you mention?
Find the conditions and treatment history the medicine leaflets ask about.
What to tell your doctorPregnancy or contraception?
Read the medicine-specific information on contraception and planning a pregnancy.
Contraception and pregnancyAn operation or procedure coming up?
Find the leaflet and NHS wording about surgery and sedation.
Surgery, sedation and the dentist
Find a guide
Search by medicine, symptom or question.
15 guides in treatment safety
Missed a dose?
What the Mounjaro, Wegovy and Ozempic leaflets and Zepbound’s label say about a missed weekly jab, word for word.
Checked against 6 sources on 12 October 2026
Read the guideStomach pain: when it’s serious
What the leaflets and the NHS say severe stomach pain can be a sign of, and what they say to do about it.
Checked against 7 sources on 12 October 2026
Read the guideLow blood sugar on a GLP-1
Who the leaflets say is most at risk of low blood sugar, the warning signs they list, and what may change.
Checked against 6 sources on 12 October 2026
Read the guideEyesight changes on a GLP-1
What the leaflets say about diabetic eye disease, the very rare NAION on semaglutide, and when to contact a doctor.
Checked against 6 sources on 12 October 2026
Read the guideAllergic reactions on a GLP-1
The signs of a serious allergic reaction the NHS lists, how rare the leaflets say it is, and what they say to do.
Checked against 6 sources on 12 October 2026
Read the guideHeadaches and dizziness
Which leaflets list headaches and dizziness, how common each is, and what the NHS says about driving.
Checked against 6 sources on 12 October 2026
Read the guideGallstones and the gallbladder
How common gallstones are on each medicine, what Zepbound’s trials found, and the signs its label lists.
Checked against 6 sources on 12 October 2026
Read the guideFeeling tired on a GLP-1
How common tiredness is on each medicine, what Zepbound’s trials found, and when Wegovy’s leaflet says it eases.
Checked against 6 sources on 12 October 2026
Read the guideSurgery, sedation and the dentist
What the leaflets and the NHS say to tell your doctor or dentist before an operation, an anaesthetic or sedation.
Checked against 6 sources on 12 October 2026
Read the guideTaking it with other medicines
The medicines the leaflets and the NHS name, from warfarin and insulin to the pill, and what they say about each.
Checked against 8 sources on 12 October 2026
Read the guideDisposing of pens and needles
Used needles, empty pens and sharps bins: the UK disposal guidance for Mounjaro and Wegovy.
Checked against 5 sources on 20 October 2026
Read the guideDriving on a GLP-1
What the leaflets and the NHS say about driving: dizziness, vision problems and low blood sugar.
Checked against 6 sources on 12 October 2026
Read the guideContraception and pregnancy
Tirzepatide and the pill, extra contraception after a dose increase, and pregnancy and breastfeeding.
Checked against 6 sources on 12 October 2026
Read the guideWhat to tell your doctor
The things the leaflets ask you to raise with your doctor before and during treatment, word for word.
Checked against 6 sources on 12 October 2026
Read the guideStopping or taking a break
What the NHS and the leaflets say about stopping, and how long semaglutide stays after a last dose.
Checked against 9 sources on 12 October 2026
Read the guide