Surgery, sedation and the dentist
Mounjaro’s, Wegovy’s and Ozempic’s leaflets ask you to tell your doctor if you’re due surgery under anaesthesia. The NHS says tell the healthcare professional about a general anaesthetic or sedative, at the dentist too. Zepbound’s label says tell all your providers before planned procedures.
In their own words
Each source’s own line, quoted as written. The three UK leaflets use near-identical words, each naming its own medicine, as do the two NHS pages.
| Source | What it says |
|---|---|
| Mounjaro | If you know that you are due to have surgery where you will be under anaesthesia (sleeping), please tell your doctor that you are using Mounjaro.Mounjaro KwikPen patient leaflet |
| Wegovy | If you know that you are due to have surgery where you will be under anaesthesia (sleeping), please tell your doctor that you are taking wegovy®.Wegovy FlexTouch patient leaflet |
| Ozempic | If you know that you are due to have surgery where you will be under anaesthesia (sleeping), please tell your doctor that you are taking Ozempic®.Ozempic patient leaflet |
| Zepbound | Tell all your healthcare providers that you are taking ZEPBOUND before you are scheduled to have surgery or other procedures.Zepbound prescribing information |
| NHS (semaglutide) | a general anaesthetic (which puts you to sleep) or a sedative (which relaxes you) for an operation or dental procedure – tell the healthcare professional that you're using semaglutideNHS: Semaglutide |
| NHS (tirzepatide) | a general anaesthetic (which puts you to sleep) or a sedative (which relaxes you) for an operation or dental procedure – tell the healthcare professional that you're using tirzepatideNHS: Tirzepatide |
Why they ask
Food in the lungs
Zepbound’s label lists food or liquid getting into the lungs in surgery or procedures that use anaesthesia or deep sedation.
A slower stomach
Zepbound’s label says it slows stomach emptying, and may raise the chance of food getting into your lungs in surgery.
Rare, despite fasting
Zepbound’s label cites rare reports of aspiration on GLP-1s under anaesthesia or deep sedation, despite reported fasting.
At the dentist too
The NHS includes dental work: before a sedative or general anaesthetic, tell the healthcare professional you use it.
Questions
Should I stop before surgery?
None of these sources tells you to stop before a procedure. They say tell your doctor, or the healthcare professional, that you use it. The NHS says talk to your doctor if you want to stop.
Does it count for the dentist?
Yes, for a general anaesthetic or a sedative. The NHS names dental procedures, and says tell the healthcare professional that you’re using it.
Why does it matter?
Zepbound’s label says it delays stomach emptying, and there have been rare reports, in people on GLP-1 medicines, of food getting into the lungs under general anaesthesia or deep sedation during planned procedures.
Diary
Your next dose, ready to mention.
Coming Up on the Diary shows your next dose with its day and time, so it’s to hand when you tell the team. Dose reminders never name your medicine on the Lock Screen.

Sources
- Mounjaro KwikPen patient leaflet
- Wegovy FlexTouch patient leaflet
- Ozempic patient leaflet
- Zepbound prescribing information
- NHS: Semaglutide
- NHS: Tirzepatide
General information, not medical advice. Follow your prescriber’s guidance.
Getting real advice
We’re not doctors. This page sums up what the NHS and the official medicine information say, and can’t tell you what’s right for your body: your prescriber’s instructions and the leaflet in your box come first. More in our terms.
- Quoted from official sources, each one linked
- Sources checked 12 October 2026
- No dosing advice; your prescriber comes first
- A pharmacist, your doctor or NHS 111If you’re not sure how to use your medicine, or a side effect bothers you or won’t go away. NHS 111 if you think you might be having serious side effects, or you’ve used too much.NHS: SemaglutideNHS: TirzepatideNHS 111 online
- Report a side effectAnyone can, not only doctors.Yellow Card (UK)MedWatch (US)