Red, itchy or sore where you inject

The NHS lists itchy or red skin where you inject as a common side effect, and Mounjaro’s and Wegovy’s leaflets call injection site reactions common, up to 1 in 10 people. The NHS lists an allergic reaction as serious, with symptoms such as a swollen throat or tongue, a raised, itchy rash or difficulty breathing.

Itchy or redA different spot next time

In their own words

What each source lists as injection site reactions, and how often it says they happen.

SourceWhat it listsHow often
MounjaroInjection site reactions (e.g. itching or redness)Mounjaro KwikPen patient leafletCommon (may affect up to 1 in 10 people)Mounjaro KwikPen patient leaflet
Wegovyinjection site reactionsWegovy FlexTouch patient leafletCommon: may affect up to 1 in 10 peopleWegovy FlexTouch patient leaflet
Ozempicsuch as bruising, pain, irritation, itching and rashOzempic patient leafletUncommon (may affect up to 1 in 100 people)Ozempic patient leaflet
NHSitchy or red skin where you injectNHS: SemaglutideCommon for both

Worth knowing

  • A new spot each week

    The NHS says change the place you inject each week; the same area is fine, just not the exact same spot each time.

  • On darker skin

    The NHS lists itchy or red skin where you inject, and notes redness may be harder to see on brown or black skin.

  • A little blood

    If blood appears where you injected, Wegovy’s and Ozempic’s patient leaflets say press lightly on the spot.

  • Pain where you inject

    Mounjaro’s leaflet lists injection site pain as an uncommon side effect, which may affect up to 1 in 100 people.

Questions

Is a red, itchy patch normal?

The NHS lists itchy or red skin where you inject among the common side effects, and says speak to a pharmacist or doctor if a side effect bothers you or does not go away.

When is it something more serious?

The NHS lists an allergic reaction among the serious side effects, with symptoms such as a swollen throat or tongue, a raised, itchy rash or difficulty breathing. The NHS says call 111 if you think you might be having serious side effects.

Does moving the spot help?

The sources don’t say it prevents reactions. They do say to change the spot each time: the NHS each week, Mounjaro’s leaflet, if you use the same area, a different spot within it, and Wegovy’s not the same spot as last time.

Injection areas

Jabwise suggests where to inject next.

Log the area with each jab and Jabwise suggests the one you’ve used longest ago, on a simple body map, so moving the spot each week takes no remembering.

Jabwise Injection Area map with six areas and Left Stomach suggested

Sources

General information, not medical advice. Follow your prescriber’s guidance.

Getting real advice

We’re not doctors. This page sums up what the NHS and the official medicine information say, and can’t tell you what’s right for your body: your prescriber’s instructions and the leaflet in your box come first. More in our terms.

  • Quoted from official sources, each one linked
  • Sources checked 12 October 2026
  • No dosing advice; your prescriber comes first