Jabwise

Heartburn, burping and indigestion

All four list them. Mounjaro’s, Wegovy’s and Ozempic’s leaflets each call indigestion, burping and reflux or heartburn common, up to 1 in 10 people. In two Zepbound trials, indigestion was reported by 9% to 10% of people on it, against 4% on placebo, and reflux and burping by 4% to 5%.

Zepbound’s trials: placebo against 15mgIndigestion4%10%Reflux2%5%Burping1%5%

In their own words

Each source’s own name for them, quoted as written. Mounjaro’s, Wegovy’s and Ozempic’s leaflets list all three as common side effects.

MedicineIndigestionBurpingReflux or heartburn
MounjaroIndigestion (dyspepsia)Mounjaro KwikPen patient leafletBurping (eructation)Mounjaro KwikPen patient leafletReflux or heartburn (also called gastroesophageal reflux disease – GORD)Mounjaro KwikPen patient leaflet
ZepboundindigestionZepbound prescribing informationbelchingZepbound prescribing informationheartburnZepbound prescribing information
Wegovyupset stomach or indigestionWegovy FlexTouch patient leafletburpingWegovy FlexTouch patient leafletreflux or heartburn – also called ‘gastro-oesophageal reflux disease’Wegovy FlexTouch patient leaflet
OzempicIndigestionOzempic patient leafletBurpingOzempic patient leafletReflux or heartburn – also called ‘gastro-esophageal reflux disease’ (GERD)Ozempic patient leaflet

What else they say

  • What reflux is

    Mounjaro’s leaflet says reflux is caused by stomach acid coming up into the tube from your stomach to your mouth.

  • An inflamed stomach

    Wegovy and Ozempic also list gastritis, an inflamed stomach, with signs like stomach ache, feeling sick or being sick.

  • In Zepbound’s trials

    Indigestion was reported by 9% to 10% on Zepbound, against 4% on placebo; burping by 4% to 5%, against 1%.

  • If one bothers you

    Zepbound’s label says talk to your healthcare provider if you have any side effect that bothers you or does not go away.

Questions

Does Mounjaro cause heartburn?

Its leaflet lists reflux or heartburn as common, up to 1 in 10 people, along with indigestion and burping.

Is burping a side effect of Ozempic?

Yes. Ozempic’s leaflet lists burping as common, up to 1 in 10 people. Mounjaro’s and Wegovy’s leaflets list it too, and Zepbound’s label calls it belching.

What helps?

None of these leaflets suggests a remedy. The NHS says speak to a pharmacist or doctor if a side effect bothers you or doesn’t go away; they may be able to give advice.

Side effects

Count the days heartburn is there.

The check-in has a tag for heartburn. Side Effects counts the days you felt it, over 7, 30 or 90 days, ready for your next review.

Jabwise Side Effects: constipation on 2 of 6 days with a check-in, over the last 7 days

Sources

General information, not medical advice. Follow your prescriber’s guidance.

Getting real advice

We’re not doctors. This page sums up what the NHS and the official medicine information say, and can’t tell you what’s right for your body: your prescriber’s instructions and the leaflet in your box come first. More in our terms.

  • Quoted from official sources, each one linked
  • Sources checked 12 October 2026
  • No dosing advice; your prescriber comes first