# Taking it with other medicines

> Tell your doctor, pharmacist or nurse about other medicines, Mounjaro’s, Wegovy’s and Ozempic’s leaflets say. The NHS names warfarin, insulin, other diabetes medicines and, for semaglutide, levothyroxine. Wegovy’s and Ozempic’s add that warfarin may mean more blood tests, and Zepbound’s that it may affect tablets.

Canonical: https://jabwise.app/guides/other-medicines. Sources checked 12 October 2026. General information, not medical advice: follow your prescriber.

## Medicines they name

Each in the words of a source that names it, quoted as written. None of these lists is complete, and the sources ask you to mention any other medicines you take.

- **Warfarin**: What they say: "Warfarin or other similar medicines taken by mouth to reduce blood clotting (oral anti-coagulants). You may need frequent blood tests to check how quickly your blood clots." ([Ozempic patient leaflet](https://www.medicines.org.uk/emc/product/9748/pil))
- **Insulin**: What they say: "insulin – your doctor or specialist nurse may need to adjust your dose" ([NHS: Tirzepatide](https://www.nhs.uk/medicines/tirzepatide/))
- **Diabetes medicines**: What they say: "other diabetes medicines, such as gliclazide, glimepiride, metformin and tolbutamide" ([NHS: Tirzepatide](https://www.nhs.uk/medicines/tirzepatide/))
- **Levothyroxine**: What they say: "levothyroxine, for an underactive thyroid" ([NHS: Semaglutide](https://www.nhs.uk/medicines/semaglutide/))
- **The pill**: What they say: "Birth control pills by mouth may not work as well while using ZEPBOUND." ([Zepbound prescribing information](https://uspl.lilly.com/zepbound/zepbound.html))
- **Other tablets**: What they say: "ZEPBOUND delays gastric emptying and thereby has the potential to impact the absorption of concomitantly administered oral medications." ([Zepbound prescribing information](https://uspl.lilly.com/zepbound/zepbound.html))

## What they ask

- **Everything you take**: Ozempic’s leaflet includes herbal medicines and ones bought without a prescription; the NHS adds vitamins and supplements.
- **On insulin**: Ozempic’s leaflet says your doctor will tell you how to reduce the dose, and recommend checking your blood sugar more often.
- **Contraception**: The NHS says use extra barrier contraception, like condoms, for 4 weeks after starting tirzepatide and each increase.
- **Rybelsus tablets**: Both Rybelsus leaflets say wait at least 30 minutes after it before eating, drinking or taking other oral medicines.

## Questions

### Can I take it with metformin?

The NHS names metformin among other diabetes medicines that may not mix well with tirzepatide or semaglutide. The NHS says tell your doctor or a pharmacist before you use it.

### Does Mounjaro affect the pill?

Mounjaro’s leaflet says women with obesity or overweight on oral contraceptives should consider also using a barrier method, or switching to a non-oral one, for 4 weeks after starting and after each increase.

### Who should I tell?

Your doctor, pharmacist or nurse, say the Mounjaro, Wegovy and Ozempic leaflets (Rybelsus’s: doctor or pharmacist), about any medicine you use, have recently used or might use.

## In Jabwise: Appointment Report

Take your record to the review. Jabwise turns your doses, weight and check-ins into a PDF for your GP or doctor, over a week, a month or longer. It states only what you logged.

## Getting real advice

- **A pharmacist, your doctor or NHS 111**: If you’re not sure how to use your medicine, or a side effect bothers you or won’t go away. NHS 111 if you think you might be having serious side effects, or you’ve used too much. [NHS: Semaglutide](https://www.nhs.uk/medicines/semaglutide/), [NHS: Tirzepatide](https://www.nhs.uk/medicines/tirzepatide/), [NHS 111 online](https://111.nhs.uk/)
- **Report a side effect**: Anyone can, not only doctors. [Yellow Card (UK)](https://yellowcard.mhra.gov.uk/), [MedWatch (US)](https://www.fda.gov/safety/medwatch-fda-safety-information-and-adverse-event-reporting-program)

## Sources

- [Mounjaro KwikPen patient leaflet](https://www.medicines.org.uk/emc/product/15481/pil)
- [Wegovy FlexTouch patient leaflet](https://www.medicines.org.uk/emc/product/13800/pil)
- [Ozempic patient leaflet](https://www.medicines.org.uk/emc/product/9748/pil)
- [Zepbound prescribing information](https://uspl.lilly.com/zepbound/zepbound.html)
- [Rybelsus 3, 7 and 14mg patient leaflet](https://www.medicines.org.uk/emc/product/11507/pil)
- [Rybelsus 1.5, 4 and 9mg patient leaflet](https://www.medicines.org.uk/emc/product/101229/pil)
- [NHS: Semaglutide](https://www.nhs.uk/medicines/semaglutide/)
- [NHS: Tirzepatide](https://www.nhs.uk/medicines/tirzepatide/)