# Eyesight changes on a GLP-1

> Wegovy’s and Ozempic’s leaflets say urgently contact your doctor if you notice a sudden loss of vision or rapidly worsening eyesight, which may be NAION, a very rare side effect. Wegovy’s leaflet and Zepbound’s label say fast improvements in blood sugar can temporarily worsen diabetic eye disease.

Canonical: https://jabwise.app/guides/eyesight-changes. Sources checked 12 October 2026. General information, not medical advice: follow your prescriber.

## If you have diabetic eye disease

What each says about diabetic eye disease, quoted as written. Mounjaro’s lists it among things to tell your doctor before you start.

- **Mounjaro**: What it says: "you have a problem with your eyes (diabetic retinopathy or macular oedema)." ([Mounjaro KwikPen patient leaflet](https://www.medicines.org.uk/emc/product/15481/pil))
- **Zepbound**: What it says: "Temporary worsening of diabetic retinopathy has been reported with rapid improvement in glucose control." ([Zepbound prescribing information](https://uspl.lilly.com/zepbound/zepbound.html))
- **Wegovy**: What it says: "Fast improvements in blood sugar control may lead to a temporary worsening of diabetic eye disease. If you have diabetic eye disease and experience eye problems while taking this medicine, talk to your doctor." ([Wegovy FlexTouch patient leaflet](https://www.medicines.org.uk/emc/product/13800/pil))
- **Ozempic**: What it says: "Tell your doctor if you have diabetic eye disease or if you experience eye problems during treatment with this medicine." ([Ozempic patient leaflet](https://www.medicines.org.uk/emc/product/9748/pil))

## Sudden changes to your eyesight

- **Sudden loss of vision**: Wegovy’s and Ozempic’s leaflets say urgently contact your doctor about sudden vision loss or rapidly worsening eyesight.
- **NAION, very rare**: The same leaflets list NAION, an eye condition that may cause loss of vision without any pain, as up to 1 in 10,000.
- **An eye examination**: If it may be NAION, they say your doctor will refer you for an eye examination, and you may have to stop treatment.
- **Driving**: The NHS says if you have vision problems after using it, don’t drive, ride a bike or use machinery until they’ve gone.

## Questions

### Can Ozempic affect your eyes?

Ozempic’s leaflet lists complications of diabetic eye disease as common, up to 1 in 10 people, and NAION as very rare, up to 1 in 10,000.

### Does Mounjaro cause NAION?

Mounjaro’s leaflet and Zepbound’s label don’t list it. Mounjaro’s asks you to tell your doctor before you start if you have diabetic retinopathy or macular oedema.

### What does the NHS say?

The NHS semaglutide page lists sudden loss of vision, usually in one eye at a time, among serious side effects, and says call 111 if you think you’re having one.

## In Jabwise: Appointment Report

Bring your dose history to the appointment. Jabwise turns your doses, dose changes and weight into a PDF for your GP or doctor, over a week, a month or longer. It states only what you logged.

## Getting real advice

- **A pharmacist, your doctor or NHS 111**: If you’re not sure how to use your medicine, or a side effect bothers you or won’t go away. NHS 111 if you think you might be having serious side effects, or you’ve used too much. [NHS: Semaglutide](https://www.nhs.uk/medicines/semaglutide/), [NHS: Tirzepatide](https://www.nhs.uk/medicines/tirzepatide/), [NHS 111 online](https://111.nhs.uk/)
- **Report a side effect**: Anyone can, not only doctors. [Yellow Card (UK)](https://yellowcard.mhra.gov.uk/), [MedWatch (US)](https://www.fda.gov/safety/medwatch-fda-safety-information-and-adverse-event-reporting-program)

## Sources

- [Mounjaro KwikPen patient leaflet](https://www.medicines.org.uk/emc/product/15481/pil)
- [Zepbound prescribing information](https://uspl.lilly.com/zepbound/zepbound.html)
- [Wegovy FlexTouch patient leaflet](https://www.medicines.org.uk/emc/product/13800/pil)
- [Ozempic patient leaflet](https://www.medicines.org.uk/emc/product/9748/pil)
- [NHS: Semaglutide](https://www.nhs.uk/medicines/semaglutide/)
- [NHS: Tirzepatide](https://www.nhs.uk/medicines/tirzepatide/)